BIOCOMPATIBILITY The term biocompatibility refers to the ability of a material to be in contact with living tissue and not cause toxic or injurious effects. In our usage, the term specifically relates to the relation of living cells to foreign substance such as metals and alloys. Standards for the biocompatibility of dental alloys are still to be determined. Both the ISO and ADA have published guidelines and have suggested a series of tests to ascertain that a medical device is biocompatible. Both organizations recommend cytotoxicity as a screening test for dental materials. The goal of all biocompatibility testing is to simulate conditions that would exist in the oral environment. Cytotoxicity
per ASTM F813-83 (1988) |
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